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Three-Dimensional Collagen Type I Matrix Up-Regulates Nuclear Isoforms of the Microtubule Associated Protein Tau Implicated in Resistance to Paclitaxel Therapy in Ovarian Carcinoma

Epithelial ovarian carcinoma is the deadliest gynecologic malignancy. One reason underlying treatment failure is resistance to paclitaxel. Expression of the microtubule associated protein tau has recently been proposed as a predictor of response to paclitaxel in ovarian carcinoma patients. Expressio...

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Detalles Bibliográficos
Autores principales: Gurler, Hilal, Yu, Yi, Choi, Jacqueline, Kajdacsy-Balla, Andre A., Barbolina, Maria V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346904/
https://www.ncbi.nlm.nih.gov/pubmed/25658796
http://dx.doi.org/10.3390/ijms16023419