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Valproic Acid as a Potential Inhibitor of Plasmodium falciparum Histone Deacetylase 1 (PfHDAC1): An in Silico Approach

A new Plasmodium falciparum histone deacetylase1 (PfHDAC1) homology model was built based on the highest sequence identity available template human histone deacetylase 2 structure. The generated model was carefully evaluated for stereochemical accuracy, folding correctness and overall structure qual...

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Detalles Bibliográficos
Autores principales: Elbadawi, Mohamed A. Abdallah, Awadalla, Mohamed Khalid Alhaj, Abdel Hamid, Muzamil Mahdi, Mohamed, Magdi Awadalla, Awad, Talal Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346934/
https://www.ncbi.nlm.nih.gov/pubmed/25679451
http://dx.doi.org/10.3390/ijms16023915