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Development of Biodegradable Nanocarriers Loaded with a Monoclonal Antibody

Treatments utilizing monoclonal antibody therapeutics against intracellular protein-protein interactions in cancer cells have been hampered by several factors, including poor intracellular uptake and rapid lysosomal degradation. Our current work examines the feasibility of encapsulating monoclonal a...

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Detalles Bibliográficos
Autores principales: Gdowski, Andrew, Ranjan, Amalendu, Mukerjee, Anindita, Vishwanatha, Jamboor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346939/
https://www.ncbi.nlm.nih.gov/pubmed/25690029
http://dx.doi.org/10.3390/ijms16023990