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Compound Danshen tablets downregulate amyloid protein precursor mRNA expression in a transgenic cell model of Alzheimer's disease: Effects and a comparison with donepezil☆

After gene mutation, the pcDNA3.1/APP595/596 plasmid was transfected into HEK293 cells to establish a cell model of Alzheimer's disease. The cell model was treated with donepezil or compound Danshen tablets after culture for 72 hours. Reverse transcription-PCR showed that the mRNA expression of...

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Detalles Bibliográficos
Autores principales: Qin, Ren’an, Zhou, Desheng, Wang, Jiajun, Hu, Hua, Yang, Yang, Yao, Xiaoxuan, Sun, Xiaopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347004/
https://www.ncbi.nlm.nih.gov/pubmed/25745459
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.09.003