Cargando…

Ultrasensitive quantification of TAP-dependent antigen compartmentalization in scarce primary immune cell subsets

Presentation of peptides on major histocompatibility complex class I (MHC I) is essential for the establishment and maintenance of self-tolerance, priming of antigen-specific CD8(+) T cells and the exertion of several T-cell effector functions. Cytosolic proteasomes continuously degrade proteins int...

Descripción completa

Detalles Bibliográficos
Autores principales: Fischbach, Hanna, Döring, Marius, Nikles, Daphne, Lehnert, Elisa, Baldauf, Christoph, Kalinke, Ulrich, Tampé, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347055/
https://www.ncbi.nlm.nih.gov/pubmed/25656091
http://dx.doi.org/10.1038/ncomms7199