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Ultrasensitive quantification of TAP-dependent antigen compartmentalization in scarce primary immune cell subsets

Presentation of peptides on major histocompatibility complex class I (MHC I) is essential for the establishment and maintenance of self-tolerance, priming of antigen-specific CD8(+) T cells and the exertion of several T-cell effector functions. Cytosolic proteasomes continuously degrade proteins int...

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Detalles Bibliográficos
Autores principales:	Fischbach, Hanna, Döring, Marius, Nikles, Daphne, Lehnert, Elisa, Baldauf, Christoph, Kalinke, Ulrich, Tampé, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347055/ https://www.ncbi.nlm.nih.gov/pubmed/25656091 http://dx.doi.org/10.1038/ncomms7199

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