Collaborative rewiring of the pluripotency network by chromatin and signalling modulating pathways

Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) represents a profound change in cell fate. Here, we show that combining ascorbic acid (AA) and 2i (MAP kinase and GSK inhibitors) increases the efficiency of reprogramming from fibroblasts and synergistically enhances conversio...

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Detalles Bibliográficos
Autores principales: Tran, Khoa A., Jackson, Steven A., Olufs, Zachariah P.G., Zaidan, Nur Zafirah, Leng, Ning, Kendziorski, Christina, Roy, Sushmita, Sridharan, Rupa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347202/
https://www.ncbi.nlm.nih.gov/pubmed/25650115
http://dx.doi.org/10.1038/ncomms7188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347202/
https://www.ncbi.nlm.nih.gov/pubmed/25650115
http://dx.doi.org/10.1038/ncomms7188

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