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Structural characterization of a protective epitope spanning A(H1N1)pdm09 influenza virus neuraminidase monomers

A(H1N1)pdm09 influenza A viruses predominated in the 2013–2014 USA influenza season, and although most of these viruses remain sensitive to Food and Drug Administration-approved neuraminidase (NA) inhibitors, alternative therapies are needed. Here we show that monoclonal antibody CD6, selected for b...

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Detalles Bibliográficos
Autores principales: Wan, Hongquan, Yang, Hua, Shore, David A., Garten, Rebecca J., Couzens, Laura, Gao, Jin, Jiang, Lianlian, Carney, Paul J., Villanueva, Julie, Stevens, James, Eichelberger, Maryna C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347215/
https://www.ncbi.nlm.nih.gov/pubmed/25668439
http://dx.doi.org/10.1038/ncomms7114