Current Understanding of BRAF Alterations in Diagnosis, Prognosis, and Therapeutic Targeting in Pediatric Low-Grade Gliomas

The mitogen-activated protein kinase (MAPK) pathway is known to play a key role in the initiation and maintenance of many tumors as well as normal development. This often occurs through mutation of the genes encoding RAS and RAF proteins which are involved in signal transduction in this pathway. BRA...

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Detalles Bibliográficos
Autores principales: Penman, Catherine Louise, Faulkner, Claire, Lowis, Stephen P., Kurian, Kathreena M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347423/
https://www.ncbi.nlm.nih.gov/pubmed/25785246
http://dx.doi.org/10.3389/fonc.2015.00054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347423/
https://www.ncbi.nlm.nih.gov/pubmed/25785246
http://dx.doi.org/10.3389/fonc.2015.00054

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