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Incorporation of membrane-anchored flagellin or Escherichia coli heat-labile enterotoxin B subunit enhances the immunogenicity of rabies virus-like particles in mice and dogs

Rabies remains an important worldwide public health threat, so safe, effective, and affordable vaccines are still being sought. Virus-like particle-based vaccines targeting various viral pathogens have been successfully produced, licensed, and commercialized. Here, we designed and constructed two ch...

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Detalles Bibliográficos
Autores principales: Qi, Yinglin, Kang, Hongtao, Zheng, Xuexing, Wang, Hualei, Gao, Yuwei, Yang, Songtao, Xia, Xianzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347500/
https://www.ncbi.nlm.nih.gov/pubmed/25784906
http://dx.doi.org/10.3389/fmicb.2015.00169