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Synthetic signal sequences that enable efficient secretory protein production in the yeast Kluyveromyces marxianus
BACKGROUND: Targeting of cellular proteins to the extracellular environment is directed by a secretory signal sequence located at the N-terminus of a secretory protein. These signal sequences usually contain an N-terminal basic amino acid followed by a stretch containing hydrophobic residues, althou...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347551/ https://www.ncbi.nlm.nih.gov/pubmed/25889890 http://dx.doi.org/10.1186/s12934-015-0203-y |