Synthetic signal sequences that enable efficient secretory protein production in the yeast Kluyveromyces marxianus

BACKGROUND: Targeting of cellular proteins to the extracellular environment is directed by a secretory signal sequence located at the N-terminus of a secretory protein. These signal sequences usually contain an N-terminal basic amino acid followed by a stretch containing hydrophobic residues, althou...

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Detalles Bibliográficos
Autores principales: Yarimizu, Tohru, Nakamura, Mikiko, Hoshida, Hisashi, Akada, Rinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347551/
https://www.ncbi.nlm.nih.gov/pubmed/25889890
http://dx.doi.org/10.1186/s12934-015-0203-y

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