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Characterization of an Ebosin derivative produced by heterologous gene replacement in Streptomyces sp. 139

BACKGROUND: Ebosin is a novel exopolysaccharide (EPS) produced by Streptomyces sp. 139 and evidenced to possess an anti-rheumatic arthritis activity in vivo. The Ebosin biosynthesis gene cluster (ste) consists of 27 ORFs and ste7 has previously been demonstrated to code for a fucosyltransferase, whi...

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Detalles Bibliográficos
Autores principales: Zhang, Yang, Shan, Junjie, Bao, Yonggang, Bai, Liping, Jiang, Rong, Guo, Lianhong, Yao, Chen, Zhang, Ren, Li, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347597/
https://www.ncbi.nlm.nih.gov/pubmed/25048214
http://dx.doi.org/10.1186/s12934-014-0103-6