An integrated approach of gene expression and DNA-methylation profiles of WNT signaling genes uncovers novel prognostic markers in Acute Myeloid Leukemia

BACKGROUND: The wingless-Int (WNT) pathway has an essential role in cell regulation of hematopoietic stem cells (HSC). For Acute Myeloid Leukemia (AML), the malignant counterpart of HSC, currently only a selective number of genes of the WNT pathway are analyzed by using either gene expression or DNA...

Descripción completa

Detalles Bibliográficos
Autores principales: Taskesen, Erdogan, Staal, Frank JT, Reinders, Marcel JT
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347618/
https://www.ncbi.nlm.nih.gov/pubmed/25734857
http://dx.doi.org/10.1186/1471-2105-16-S4-S4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347618/
https://www.ncbi.nlm.nih.gov/pubmed/25734857
http://dx.doi.org/10.1186/1471-2105-16-S4-S4

Ejemplares similares