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An integrated approach of gene expression and DNA-methylation profiles of WNT signaling genes uncovers novel prognostic markers in Acute Myeloid Leukemia

BACKGROUND: The wingless-Int (WNT) pathway has an essential role in cell regulation of hematopoietic stem cells (HSC). For Acute Myeloid Leukemia (AML), the malignant counterpart of HSC, currently only a selective number of genes of the WNT pathway are analyzed by using either gene expression or DNA...

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Detalles Bibliográficos
Autores principales:	Taskesen, Erdogan, Staal, Frank JT, Reinders, Marcel JT
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347618/ https://www.ncbi.nlm.nih.gov/pubmed/25734857 http://dx.doi.org/10.1186/1471-2105-16-S4-S4

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