DNA2 drives processing and restart of reversed replication forks in human cells

Accurate processing of stalled or damaged DNA replication forks is paramount to genomic integrity and recent work points to replication fork reversal and restart as a central mechanism to ensuring high-fidelity DNA replication. Here, we identify a novel DNA2- and WRN-dependent mechanism of reversed...

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Detalles Bibliográficos
Autores principales: Thangavel, Saravanabhavan, Berti, Matteo, Levikova, Maryna, Pinto, Cosimo, Gomathinayagam, Shivasankari, Vujanovic, Marko, Zellweger, Ralph, Moore, Hayley, Lee, Eu Han, Hendrickson, Eric A., Cejka, Petr, Stewart, Sheila, Lopes, Massimo, Vindigni, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347643/
https://www.ncbi.nlm.nih.gov/pubmed/25733713
http://dx.doi.org/10.1083/jcb.201406100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347643/
https://www.ncbi.nlm.nih.gov/pubmed/25733713
http://dx.doi.org/10.1083/jcb.201406100

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