DENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior

The small guanosine triphosphatase Rab13 functions in exocytic vesicle trafficking in epithelial cells. Alterations in Rab13 activity have been observed in human cancers, yet the mechanism of Rab13 activation and its role in cancer progression remain unclear. In this paper, we identify the DENN doma...

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Detalles Bibliográficos
Autores principales: Ioannou, Maria S., Bell, Emily S., Girard, Martine, Chaineau, Mathilde, Hamlin, Jason N.R., Daubaras, Mark, Monast, Anie, Park, Morag, Hodgson, Louis, McPherson, Peter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347646/
https://www.ncbi.nlm.nih.gov/pubmed/25713415
http://dx.doi.org/10.1083/jcb.201407068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347646/
https://www.ncbi.nlm.nih.gov/pubmed/25713415
http://dx.doi.org/10.1083/jcb.201407068

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