Desensitization and immune tolerance induction in children with severe factor IX deficiency; inhibitors and adverse reactions to replacement therapy: a case-report and literature review

Hemophilia B is a rare X-linked recessive disorder with plasma factor IX (FIX) deficiency. 1-3% of patients treated with exogenous FIX-containing products develop inhibitors (i.e. polyclonal high affinity immunoglobulins) that neutralize the procoagulant activity of a specific coagulation factor. Al...

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Detalles Bibliográficos
Autores principales: Bon, Andrea, Morfini, Massimo, Dini, Alessandro, Mori, Francesca, Barni, Simona, Gianluca, Sottilotta, de Martino, Maurizio, Novembre, Elio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347657/
https://www.ncbi.nlm.nih.gov/pubmed/25887512
http://dx.doi.org/10.1186/s13052-015-0116-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347657/
https://www.ncbi.nlm.nih.gov/pubmed/25887512
http://dx.doi.org/10.1186/s13052-015-0116-8

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