TRAF6 promotes TGFβ-induced invasion and cell-cycle regulation via Lys63-linked polyubiquitination of Lys178 in TGFβ type I receptor

Transforming growth factor β (TGFβ) can act either as a tumor promoter or a tumor suppressor in a context-dependent manner. High levels of TGFβ are found in prostate cancer tissues and correlate with poor patient prognosis. We recently identified a novel TGFβ-regulated signaling cascade in which TGF...

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Detalles Bibliográficos
Autores principales: Sundar, Reshma, Gudey, Shyam Kumar, Heldin, Carl-Henrik, Landström, Marene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347693/
https://www.ncbi.nlm.nih.gov/pubmed/25622187
http://dx.doi.org/10.4161/15384101.2014.990302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347693/
https://www.ncbi.nlm.nih.gov/pubmed/25622187
http://dx.doi.org/10.4161/15384101.2014.990302

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