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Evaluation of a Triple-Helical Peptide with Quenched Fluorophores for Optical Imaging of MMP-2 and MMP-9 Proteolytic Activity

Matrix metalloproteinases (MMP) 2 and 9, the gelatinases, have consistently been associated with tumor progression. The development of gelatinase-specific probes will be critical for identifying in vivo gelatinoic activity to understand the molecular role of the gelatinases in tumor development. Rec...

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Detalles Bibliográficos
Autores principales: Zhang, Xuan, Bresee, Jamee, Cheney, Philip P., Xu, Baogang, Bhowmick, Manishabrata, Cudic, Mare, Fields, Gregg B., Edwards, Wilson Barry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347883/
https://www.ncbi.nlm.nih.gov/pubmed/24959683
http://dx.doi.org/10.3390/molecules19068571