The Cholesterol Transporter ABCG1 Links Cholesterol Homeostasis and Tumor Immunity

ATP-binding Cassette Transporter G1 (ABCG1) promotes cholesterol efflux from cells and regulates intracellular cholesterol homeostasis. Here, we demonstrate a role of ABCG1 as a mediator of tumor immunity. Abcg1(−/−) mice have dramatically suppressed subcutaneous MB49-bladder carcinoma and B16-melan...

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Detalles Bibliográficos
Autores principales: Sag, Duygu, Cekic, Caglar, Wu, Runpei, Linden, Joel, Hedrick, Catherine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347884/
https://www.ncbi.nlm.nih.gov/pubmed/25724068
http://dx.doi.org/10.1038/ncomms7354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347884/
https://www.ncbi.nlm.nih.gov/pubmed/25724068
http://dx.doi.org/10.1038/ncomms7354

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