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The Cholesterol Transporter ABCG1 Links Cholesterol Homeostasis and Tumor Immunity
ATP-binding Cassette Transporter G1 (ABCG1) promotes cholesterol efflux from cells and regulates intracellular cholesterol homeostasis. Here, we demonstrate a role of ABCG1 as a mediator of tumor immunity. Abcg1(−/−) mice have dramatically suppressed subcutaneous MB49-bladder carcinoma and B16-melan...
Autores principales: | Sag, Duygu, Cekic, Caglar, Wu, Runpei, Linden, Joel, Hedrick, Catherine C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347884/ https://www.ncbi.nlm.nih.gov/pubmed/25724068 http://dx.doi.org/10.1038/ncomms7354 |
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