Potent restriction of HIV-1 and SIV(mac239) Replication by African Green Monkey TRIM5α

BACKGROUND: The TRIM5α protein is a principal restriction factor that contributes to an HIV-1 replication block in rhesus macaque CD4(+) T cells by preventing reverse transcription. HIV-1 restriction is induced in human CD4(+) T cells by expression of rhesus TRIM5α as well as those of other old worl...

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Detalles Bibliográficos
Autores principales: Coren, Lori V, Trivett, Matthew T, Jain, Sumiti, Ayala, Victor I, Del Prete, Gregory Q, Ohlen, Claes, Ott, David E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348108/
https://www.ncbi.nlm.nih.gov/pubmed/25809491
http://dx.doi.org/10.1186/s12977-015-0137-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348108/
https://www.ncbi.nlm.nih.gov/pubmed/25809491
http://dx.doi.org/10.1186/s12977-015-0137-9

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