Minocycline upregulates cyclic AMP response element binding protein and brain-derived neurotrophic factor in the hippocampus of cerebral ischemia rats and improves behavioral deficits

BACKGROUND AND PURPOSE: The cAMP response element binding protein (CREB) plays an important role in the mechanism of cognitive impairment and is also pivotal in the switch from short-term to long-term memory. Brain-derived neurotrophic factor (BDNF) seems a promising avenue in the treatment of cereb...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Yu, Xiao, Ming, He, Wenbo, Cai, Zhiyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348135/
https://www.ncbi.nlm.nih.gov/pubmed/25750531
http://dx.doi.org/10.2147/NDT.S73836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348135/
https://www.ncbi.nlm.nih.gov/pubmed/25750531
http://dx.doi.org/10.2147/NDT.S73836

Ejemplares similares