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Minocycline upregulates cyclic AMP response element binding protein and brain-derived neurotrophic factor in the hippocampus of cerebral ischemia rats and improves behavioral deficits

BACKGROUND AND PURPOSE: The cAMP response element binding protein (CREB) plays an important role in the mechanism of cognitive impairment and is also pivotal in the switch from short-term to long-term memory. Brain-derived neurotrophic factor (BDNF) seems a promising avenue in the treatment of cereb...

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Detalles Bibliográficos
Autores principales:	Zhao, Yu, Xiao, Ming, He, Wenbo, Cai, Zhiyou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348135/ https://www.ncbi.nlm.nih.gov/pubmed/25750531 http://dx.doi.org/10.2147/NDT.S73836

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