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Nimotuzumab abrogates acquired radioresistance of KYSE-150R esophageal cancer cells by inhibiting EGFR signaling and cellular DNA repair

BACKGROUND: Acquired radioresistance of cancer is common after repeated irradiation and often leads to treatment failure. This study aimed to examine the effects of nimotuzumab on acquired radioresistance in human esophageal carcinoma cells and to investigate its underlying mechanisms. METHODS: The...

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Detalles Bibliográficos
Autores principales: Liu, Hai, Yang, Weifang, Gao, Huaping, Jiang, Tingting, Gu, Bengxin, Dong, Qinghua, Xu, Wenhong, Wu, Shixiu, Sun, Xiaonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348136/
https://www.ncbi.nlm.nih.gov/pubmed/25750543
http://dx.doi.org/10.2147/OTT.S76958