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Evidence of more ion channels inhibited by celecoxib: K(V)1.3 and L-type Ca(2+) channels
BACKGROUND: Celecoxib, a selective inhibitor of cyclooxygenase-2, can directly modulate many voltage-activated potassium, sodium and calcium channels and alter functioning of excitable cells. The inhibitory and facilitating effects of celecoxib on ion channels occur at low micromolar concentrations,...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348164/ https://www.ncbi.nlm.nih.gov/pubmed/25889233 http://dx.doi.org/10.1186/s13104-015-1023-1 |