Structure of precursor microRNA’s terminal loop regulates human Dicer’s dicing activity by switching DExH/D domain

Almost all pre-miRNAs in eukaryotic cytoplasm are recognized and processed into double-stranded microRNAs by the endonuclease Dicer protein comprising of multiple domains. As a key player in the small RNA induced gene silencing pathway, the major domains of Dicer are conserved among different specie...

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Detalles Bibliográficos
Autores principales: Liu, Zhongmin, Wang, Jia, Li, Gang, Wang, Hong-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348242/
https://www.ncbi.nlm.nih.gov/pubmed/25549615
http://dx.doi.org/10.1007/s13238-014-0124-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348242/
https://www.ncbi.nlm.nih.gov/pubmed/25549615
http://dx.doi.org/10.1007/s13238-014-0124-2

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