Cargando…

Essential role of the iron-sulfur cluster binding domain of the primase regulatory subunit Pri2 in DNA replication initiation

DNA primase catalyzes de novo synthesis of a short RNA primer that is further extended by replicative DNA polymerases during initiation of DNA replication. The eukaryotic primase is a heterodimeric enzyme comprising a catalytic subunit Pri1 and a regulatory subunit Pri2. Pri2 is responsible for faci...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Lili, Huang, Mingxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348247/
https://www.ncbi.nlm.nih.gov/pubmed/25645023
http://dx.doi.org/10.1007/s13238-015-0134-8