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Quantification of [(11)C]yohimbine binding to α(2) adrenoceptors in rat brain in vivo

We quantified the binding potentials (BP(ND)) of [(11)C]yohimbine binding in rat brain to alpha-2 adrenoceptors to evaluate [(11)C]yohimbine as an in vivo marker of noradrenergic neurotransmission and to examine its sensitivity to the level of noradrenaline. Dual [(11)C]yohimbine dynamic positron em...

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Detalles Bibliográficos
Autores principales: Phan, Jenny-Ann, Landau, Anne M, Wong, Dean F, Jakobsen, Steen, Nahimi, Adjmal, Doudet, Doris J, Gjedde, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348393/
https://www.ncbi.nlm.nih.gov/pubmed/25564241
http://dx.doi.org/10.1038/jcbfm.2014.225