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α6β1- and αV-integrins are required for long-term self-renewal of murine embryonic stem cells in the absence of LIF
BACKGROUND: The growth properties and self-renewal capacity of embryonic stem (ES) cells are regulated by their immediate microenvironment such as the extracellular matrix (ECM). Integrins, a central family of cellular ECM receptors, have been implicated in these processes but their specific role in...
Autores principales: | Cattavarayane, Sandhanakrishnan, Palovuori, Riitta, Tanjore Ramanathan, Jayendrakishore, Manninen, Aki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348401/ https://www.ncbi.nlm.nih.gov/pubmed/25886986 http://dx.doi.org/10.1186/s12860-015-0051-y |
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