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TNFα Transport Induced by Dynamic Loading Alters Biomechanics of Intact Intervertebral Discs

OBJECTIVE: Intervertebral disc (IVD) degeneration is an important contributor to the development of back pain, and a key factor relating pain and degeneration are the presence of pro-inflammatory cytokines and IVD motion. There is surprisingly limited understanding of how mechanics and inflammation...

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Detalles Bibliográficos
Autores principales: Walter, Benjamin A., Likhitpanichkul, Morakot, Illien-Junger, Svenja, Roughley, Peter J., Hecht, Andrew C., Iatridis, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348425/
https://www.ncbi.nlm.nih.gov/pubmed/25734788
http://dx.doi.org/10.1371/journal.pone.0118358