Sphingosine-1-Phosphate Mediates ICAM-1-Dependent Monocyte Adhesion through p38 MAPK and p42/p44 MAPK-Dependent Akt Activation

Up-regulation of intercellular adhesion molecule-1 (ICAM-1) is frequently implicated in lung inflammation. Sphingosine-1-phosphate (S1P) has been shown to play a key role in inflammation via adhesion molecules induction, and then causes lung injury. However, the mechanisms underlying S1P-induced ICA...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Chih-Chung, Lee, I-Ta, Hsu, Chun-Hao, Hsu, Chih-Kai, Chi, Pei-Ling, Hsiao, Li-Der, Yang, Chuen-Mao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348486/
https://www.ncbi.nlm.nih.gov/pubmed/25734900
http://dx.doi.org/10.1371/journal.pone.0118473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348486/
https://www.ncbi.nlm.nih.gov/pubmed/25734900
http://dx.doi.org/10.1371/journal.pone.0118473

Ejemplares similares