PRIMAL: Fast and Accurate Pedigree-based Imputation from Sequence Data in a Founder Population

Founder populations and large pedigrees offer many well-known advantages for genetic mapping studies, including cost-efficient study designs. Here, we describe PRIMAL (PedigRee IMputation ALgorithm), a fast and accurate pedigree-based phasing and imputation algorithm for founder populations. PRIMAL...

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Detalles Bibliográficos
Autores principales: Livne, Oren E., Han, Lide, Alkorta-Aranburu, Gorka, Wentworth-Sheilds, William, Abney, Mark, Ober, Carole, Nicolae, Dan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348507/
https://www.ncbi.nlm.nih.gov/pubmed/25735005
http://dx.doi.org/10.1371/journal.pcbi.1004139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348507/
https://www.ncbi.nlm.nih.gov/pubmed/25735005
http://dx.doi.org/10.1371/journal.pcbi.1004139

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