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PRIMAL: Fast and Accurate Pedigree-based Imputation from Sequence Data in a Founder Population
Founder populations and large pedigrees offer many well-known advantages for genetic mapping studies, including cost-efficient study designs. Here, we describe PRIMAL (PedigRee IMputation ALgorithm), a fast and accurate pedigree-based phasing and imputation algorithm for founder populations. PRIMAL...
Autores principales: | Livne, Oren E., Han, Lide, Alkorta-Aranburu, Gorka, Wentworth-Sheilds, William, Abney, Mark, Ober, Carole, Nicolae, Dan L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348507/ https://www.ncbi.nlm.nih.gov/pubmed/25735005 http://dx.doi.org/10.1371/journal.pcbi.1004139 |
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