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Development and validation of an alternative disturbed skin model by mechanical abrasion to study drug penetration
Pharmaceuticals and cosmetics for dermal application are usually tested on healthy skin, although the primary permeation barrier, the stratum corneum, is often impaired by skin diseases or small skin lesions, especially on the hands. These skin conditions can considerably influence the permeation of...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348514/ https://www.ncbi.nlm.nih.gov/pubmed/25756004 http://dx.doi.org/10.1016/j.rinphs.2014.09.002 |