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Compressive Stress Induces Dephosphorylation of the Myosin Regulatory Light Chain via RhoA Phosphorylation by the Adenylyl Cyclase/Protein Kinase A Signaling Pathway

Mechanical stress that arises due to deformation of the extracellular matrix (ECM) either stretches or compresses cells. The cellular response to stretching has been actively studied. For example, stretching induces phosphorylation of the myosin regulatory light chain (MRLC) via the RhoA/RhoA-associ...

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Detalles Bibliográficos
Autores principales: Takemoto, Kenji, Ishihara, Seiichiro, Mizutani, Takeomi, Kawabata, Kazushige, Haga, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348516/
https://www.ncbi.nlm.nih.gov/pubmed/25734240
http://dx.doi.org/10.1371/journal.pone.0117937