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Systems biology approaches for advancing the discovery of effective drug combinations

Complex diseases like cancer are regulated by large, interconnected networks with many pathways affecting cell proliferation, invasion, and drug resistance. However, current cancer therapy predominantly relies on the reductionist approach of one gene-one disease. Combinations of drugs may overcome d...

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Detalles Bibliográficos
Autores principales: Ryall, Karen A, Tan, Aik Choon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348553/
https://www.ncbi.nlm.nih.gov/pubmed/25741385
http://dx.doi.org/10.1186/s13321-015-0055-9