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Acute upregulation of hedgehog signaling in mice causes differential effects on cranial morphology

Hedgehog (HH) signaling, and particularly signaling by sonic hedgehog (SHH), is implicated in several essential activities during morphogenesis, and its misexpression causes a number of developmental disorders in humans. In particular, a reduced mitogenic response of cerebellar granule cell precurso...

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Detalles Bibliográficos
Autores principales: Singh, Nandini, Dutka, Tara, Devenney, Benjamin M., Kawasaki, Kazuhiko, Reeves, Roger H., Richtsmeier, Joan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348564/
https://www.ncbi.nlm.nih.gov/pubmed/25540129
http://dx.doi.org/10.1242/dmm.017889