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Acute upregulation of hedgehog signaling in mice causes differential effects on cranial morphology
Hedgehog (HH) signaling, and particularly signaling by sonic hedgehog (SHH), is implicated in several essential activities during morphogenesis, and its misexpression causes a number of developmental disorders in humans. In particular, a reduced mitogenic response of cerebellar granule cell precurso...
Autores principales: | Singh, Nandini, Dutka, Tara, Devenney, Benjamin M., Kawasaki, Kazuhiko, Reeves, Roger H., Richtsmeier, Joan T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348564/ https://www.ncbi.nlm.nih.gov/pubmed/25540129 http://dx.doi.org/10.1242/dmm.017889 |
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