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Transformation of an Unclassified Myeloproliferative Neoplasm with a Rare BCR-JAK2 Fusion Transcript Resulting from the Translocation (9;22)(p24;q11)

BCR-ABL1 negative myeloproliferative neoplasms (MPNs) are known to contain alterations of the tyrosine kinase JAK2 (located on 9p24) that result in constitutive activation of the encoded protein. JAK2 fusions are reported in acute and chronic leukemias of myeloid and lymphoid phenotypes. Here, we re...

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Detalles Bibliográficos
Autores principales: Chamseddine, A. N., Etancelin, P., Penther, D., Parmentier, F., Kuadjovi, C., Camus, V., Contentin, N., Lenain, P., Bastard, C., Tilly, H., Jardin, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348613/
https://www.ncbi.nlm.nih.gov/pubmed/25789185
http://dx.doi.org/10.1155/2015/252537