βA3/A1-crystallin is a critical mediator of STAT3 signaling in optic nerve astrocytes

We have previously reported that in the Nuc1 rat, which has a spontaneous mutation in Cryba1 (the gene encoding βA3/A1-crystallin), astrocytes exhibit decreased Notch signaling, leading to reduced promoter activity for glial fibrillary acidic protein (GFAP). Interestingly, in both Nuc1 astrocytes an...

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Detalles Bibliográficos
Autores principales: Valapala, Mallika, Edwards, Malia, Hose, Stacey, Hu, Jianfei, Wawrousek, Eric, Lutty, Gerard A., Zigler, Jr., J. Samuel, Qian, Jiang, Sinha, Debasish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348628/
https://www.ncbi.nlm.nih.gov/pubmed/25736717
http://dx.doi.org/10.1038/srep08755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348628/
https://www.ncbi.nlm.nih.gov/pubmed/25736717
http://dx.doi.org/10.1038/srep08755

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