N-butylidenephthalide Attenuates Alzheimer's Disease-Like Cytopathy in Down Syndrome Induced Pluripotent Stem Cell-Derived Neurons

Down syndrome (DS) patients with early-onset dementia share similar neurodegenerative features with Alzheimer's disease (AD). To recapitulate the AD cell model, DS induced pluripotent stem cells (DS-iPSCs), reprogrammed from mesenchymal stem cells in amniotic fluid, were directed toward a neuro...

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Detalles Bibliográficos
Autores principales: Chang, Chia-Yu, Chen, Sheng-Mei, Lu, Huai-En, Lai, Syu-Ming, Lai, Ping-Shan, Shen, Po-Wen, Chen, Pei-Ying, Shen, Ching-I, Harn, Horng-Jyh, Lin, Shinn-Zong, Hwang, Shiaw-Min, Su, Hong-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348654/
https://www.ncbi.nlm.nih.gov/pubmed/25735452
http://dx.doi.org/10.1038/srep08744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348654/
https://www.ncbi.nlm.nih.gov/pubmed/25735452
http://dx.doi.org/10.1038/srep08744

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