Src-Mediated EGF Receptor Activation Regulates Ozone-Induced Interleukin 8 Expression in Human Bronchial Epithelial Cells

BACKGROUND: Human exposure to ozone (O(3)) results in pulmonary function decrements and airway inflammation. The mechanisms underlying these adverse effects remain unclear. Epidermal growth factor receptor (EGFR) plays an important role in the pathogenesis of lung inflammation. OBJECTIVE: We examine...

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Detalles Bibliográficos
Autores principales: Wu, Weidong, Wages, Phillip A., Devlin, Robert B., Diaz-Sanchez, David, Peden, David B., Samet, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: NLM-Export 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348738/
https://www.ncbi.nlm.nih.gov/pubmed/25303742
http://dx.doi.org/10.1289/ehp.1307379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348738/
https://www.ncbi.nlm.nih.gov/pubmed/25303742
http://dx.doi.org/10.1289/ehp.1307379

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