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The DNA Damage Response and Checkpoint Adaptation in Saccharomyces cerevisiae: Distinct Roles for the Replication Protein A2 (Rfa2) N-Terminus

In response to DNA damage, two general but fundamental processes occur in the cell: (1) a DNA lesion is recognized and repaired, and (2) concomitantly, the cell halts the cell cycle to provide a window of opportunity for repair to occur. An essential factor for a proper DNA-damage response is the he...

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Detalles Bibliográficos
Autores principales: Ghospurkar, Padmaja L., Wilson, Timothy M., Severson, Amber L., Klein, Sarah J., Khaku, Sakina K., Walther, André P., Haring, Stuart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349066/
https://www.ncbi.nlm.nih.gov/pubmed/25595672
http://dx.doi.org/10.1534/genetics.114.173211