Structure determination of Murine Norovirus NS6 proteases with C-terminal extensions designed to probe protease–substrate interactions

Noroviruses are positive-sense single-stranded RNA viruses. They encode an NS6 protease that cleaves a viral polyprotein at specific sites to produce mature viral proteins. In an earlier study we obtained crystals of murine norovirus (MNV) NS6 protease in which crystal contacts were mediated by spec...

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Detalles Bibliográficos
Autores principales: Fernandes, Humberto, Leen, Eoin N., Cromwell Jr, Hamlet, Pfeil, Marc-Philipp, Curry, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2015
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349150/
https://www.ncbi.nlm.nih.gov/pubmed/25755927
http://dx.doi.org/10.7717/peerj.798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349150/
https://www.ncbi.nlm.nih.gov/pubmed/25755927
http://dx.doi.org/10.7717/peerj.798

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