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PD-1 expression defines two distinct T-cell sub-populations in follicular lymphoma that differentially impact patient survival
To determine the biological and clinical relevance of programmed death 1 (PD-1) in follicular lymphoma (FL), we characterized PD-1(+) T-cell subsets and assessed their biological function as well as potential clinical impact. We found that PD-1 is expressed on intratumoral CD4(+) T cells with both b...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349259/ https://www.ncbi.nlm.nih.gov/pubmed/25700246 http://dx.doi.org/10.1038/bcj.2015.1 |