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PD-1 expression defines two distinct T-cell sub-populations in follicular lymphoma that differentially impact patient survival

To determine the biological and clinical relevance of programmed death 1 (PD-1) in follicular lymphoma (FL), we characterized PD-1(+) T-cell subsets and assessed their biological function as well as potential clinical impact. We found that PD-1 is expressed on intratumoral CD4(+) T cells with both b...

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Detalles Bibliográficos
Autores principales: Yang, Z -Z, Grote, D M, Ziesmer, S C, Xiu, B, Novak, A J, Ansell, S M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349259/
https://www.ncbi.nlm.nih.gov/pubmed/25700246
http://dx.doi.org/10.1038/bcj.2015.1

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