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Cyclin E2 is the predominant E-cyclin associated with NPAT in breast cancer cells
BACKGROUND: The cyclin E oncogene activates CDK2 to drive cells from G(1) to S phase of the cell cycle to commence DNA replication. It coordinates essential cellular functions with the cell cycle including histone biogenesis, splicing, centrosome duplication and origin firing for DNA replication. Th...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349318/ https://www.ncbi.nlm.nih.gov/pubmed/25741376 http://dx.doi.org/10.1186/s13008-015-0007-9 |