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Cyclin E2 is the predominant E-cyclin associated with NPAT in breast cancer cells

BACKGROUND: The cyclin E oncogene activates CDK2 to drive cells from G(1) to S phase of the cell cycle to commence DNA replication. It coordinates essential cellular functions with the cell cycle including histone biogenesis, splicing, centrosome duplication and origin firing for DNA replication. Th...

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Detalles Bibliográficos
Autores principales: Rogers, Samuel, Gloss, Brian S, Lee, Christine S, Sergio, Claudio Marcelo, Dinger, Marcel E, Musgrove, Elizabeth A, Burgess, Andrew, Caldon, Catherine Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349318/
https://www.ncbi.nlm.nih.gov/pubmed/25741376
http://dx.doi.org/10.1186/s13008-015-0007-9