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Sequence Features and Transcriptional Stalling within Centromere DNA Promote Establishment of CENP-A Chromatin

Centromere sequences are not conserved between species, and there is compelling evidence for epigenetic regulation of centromere identity, with location being dictated by the presence of chromatin containing the histone H3 variant CENP-A. Paradoxically, in most organisms CENP-A chromatin generally o...

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Detalles Bibliográficos
Autores principales: Catania, Sandra, Pidoux, Alison L., Allshire, Robin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349457/
https://www.ncbi.nlm.nih.gov/pubmed/25738810
http://dx.doi.org/10.1371/journal.pgen.1004986